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You are here: Home > Analgesia
Choose a sub category:
Dynamic Weight Bearing Test Electronic Von Frey
Hot Plate Meter Hot/Cold Plate Meter
Incapacitance Meter Plethysmometer
Rat Paw Pressure Meter Tail Flick Meter
Thermal Gradient Test Thermal Place Preference

HOT/COLD PLATE ANALGESIA METER
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The Hot/Cold Plate Analgesia Meter can be heated to 65 and cooled to -3C with an electronic thermostat that maintains the temperature, displaying current values on the LCD display screen.  

Pain sensitivity to heat or cold is assessed by placing the animal on the an aluminum plate and starting the timer.  The operator stops the timer at the instant the animal lifts its paws from the plate, reacting from discomfort.  The front panel timer displays the latency to react, a measurement of the animal's resistance to pain.

The Hot/Cold Plate is accurate to less than 0.5C.  

System includes stimulation unit, footswitch, USB cable, software for data acquisition and user's manual.
HOT PLATE ANALGESIA METER
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The Hot Plate Analgesia Meter is used to evaluate thermal pain relfex due to footpad contact with heated surface.  During the experiments, the animal is confined in a clear, cylinder (included) where the latency to the first hind paw and/or jump response is recorded.  

This unit features a thick aluminum plate that is 10mm that provides a high temperature stability and even surface temperature distribution.  The plate temperature can be held at a set point between 45 and 62 C (-0.1C).  A built-in timer and external footswitch allows precise measurement of reaction time.  Reaction time is displayed on the LCD screen within the control unit, but also saved through the included software for data acquisition.  Trial number, plate temperature, and reaction time are all recorded as well as displayed.

System includes base with heating plate, footswitch, USB cable, software for data acquisition and user's manual.
INCAPACITANCE TEST SENSOR
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The Incapacitance Meter is ideal for assessing spontaneous pain in laboratory animal models.  The animal is placed in the appropriate specie holder, on two separated sensor plates.  The spontaneous postural changes are noted by changes in weight placed on those sensors by the animal.  In the absence of hind paw injury, the animals apply equal weight on both hind paws, exhibiting postural equilibrium.  With unilateral hind paw tissue injury, a change in the weight distribution on the sensor can be detected, a lower weight being applied by the injured paw.
INCAPACITANCE TEST HOLDER, MOUSE
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This test holder for mice is used inconjunction with the Incapacitance Test Meter.
INCAPACITANCE TEST HOLDER, RAT
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This test holder for rat is used inconjunction with the Incapacitance Test Meter.
INCAPACITANCE TEST CONTROL UNIT WITH SOFTWARE
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This control unit connects to the Incapacitance Test Meter sensor.
DIGITAL PLETHYSMOMETER
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Designed to evaluate changes in paw volume, our Digital Plethysmometer is useful to study imflammatory response in lab animals.  The volume transducer is formed by two perspex tubes interconnected and filled with a conductive solution and a platinum electrode in each chamber.  Water displacement produced by the immersion of the animal's paw in the measuring tube is reflected in the second tube, inducing a change in the conductance between the two electrodes.  The control unit detects the change in conductance and generates an output signal to the display indicating the volume displacement measured in 0.01 ml resolution.  

The system includes the control unit, volume transducer, calibrator, 100ml solution, footswitch, software for data acquisition and instruction manual.
RAT PAW PRESSURE METER
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Our Rat Paw Pressure Meter, based on the Randall and Selitto test for determining an animal's response to mechanical pain, involves the applicatoin of an increasing pressure until a response is observed.  This model gradually increases pressure applied to the paw via a step motor advancing a sliding support with distal conic tip.  A extensiometric load cell is mounted to the conic tip, measuring force applied at each moment of the test.  

This unit includes stimulation unit, footswitch, flat and pointed tips, software for data acquisition, communication cables, and instruction manual.
TAIL FLICK METER
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Our Tail Flick Meter features a radiant heat stimulus applied to the animal's tail.  When it feels discomfort, the animal reacts by a tail flick, which automatically stops the timer, recording the animal's reaction time.  This test is sensitive for studying analgesic properties of pharmaceuticals and for evaluating basal thermal pain sensitivity.  

Our Tail Flick System includes a stimulation unit with halogen lamp and an electronic control unit.  The system is suitable for both mice and rats.  The animal is placed in a restrainer (please specify species at time of order) with its tail protruding on the platform of the stimulus unit.  The animal's tail is positioned in a groove of adjustable width to ensure correct tail placement for the experiment.  An included remote footswitch controls start/stop, allowing hands-free rapid testing.  

A photo beam with adjustable sensitivity detects the tail flick and the latency is automatically presented on the digital display of the control unit.  Measurements of reaction time are giving with a 0.1 precision.  A cut-off time can be set to avoid tissue damage (by default this is 20 sec).  The groove system for the tail and the adjustment of response sensitivity ensure optimum repeatability and reliability of results.  Software is also included for easy data acquisition through an RS-232 connection.
TAIL TEMPERATURE RECORDER
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This thermometer is used in conjunction with the Tail Flick Meter to record the temperature of the animal's tail at the time of the tail flick.  The temperature, along with the latency to flick provided by the Tail Flick Meter provide complete information regarding the animal's thermal pain threshold.